Therapeutic Uses
Anti-Diabetic
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Dapagliflozin Impurity-S3A
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for complete information
Tetra acetyl Dapagliflozin is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Tetra acetyl Dapagliflozin usage and description
Tetra acetyl Dapagliflozin is a synthetic compound that belongs to the class of sodium-glucose cotransporter 2 (SGLT2) inhibitors. It is a prodrug of dapagliflozin, which is used to treat type 2 diabetes mellitus. The tetra acetylation of dapagliflozin increases its solubility and bioavailability, making it more effective than dapagliflozin alone.
Tetra acetyl Dapagliflozin works by inhibiting the SGLT2 transporter in the kidneys, which is responsible for reabsorbing glucose from the urine back into the bloodstream. By inhibiting this transporter, the drug increases the amount of glucose excreted in the urine, leading to a decrease in blood glucose levels.
The chemical formula of Tetra acetyl Dapagliflozin is C25H30O10, with a molecular weight of 490.50 g/mol. It is a white to off-white crystalline powder that is soluble in water, ethanol, and dimethyl sulfoxide.
Tetra acetyl Dapagliflozin is administered orally as a tablet, with a recommended dose of 10 mg once daily. The drug is metabolized in the liver and excreted in the urine, with a half-life of approximately 12 hours.
Overall, Tetra acetyl Dapagliflozin is a safe and effective drug for the management of type 2 diabetes mellitus, with a low risk of adverse effects. However, it should be used with caution in patients with renal impairment or dehydration, as it may increase the risk of kidney injury.