Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
5-(4-bromophenyl)-6-[2-(5-bromopyrimidin-2-yl)oxy-1,1,2,2-tetradeuterioethoxy]-N-(propylsulfamoyl)pyrimidin-4-amine
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 95 %
Hazard Compound
No -Refer MSDS for accurate information
Macitentan-d4 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
always, we appreciate your support.
Macitentan-d4 usage and description
Macitentan D4 is a deuterated form of macitentan, a medication used to treat pulmonary arterial hypertension (PAH). PAH is a condition characterized by high blood pressure in the arteries of the lungs, which can lead to heart failure and other complications. Macitentan D4 works by blocking the action of endothelin, a substance that constricts blood vessels and increases blood pressure.
Macitentan D4 is administered orally, typically in tablet form, with or without food. The recommended dosage is usually once daily, but this may vary depending on the severity of the condition and the individual patient's response to treatment. It is important to follow the dosage instructions provided by the healthcare provider and to not exceed the recommended dose.
Macitentan D4 is a stable isotope-labeled compound, meaning that it contains a higher proportion of deuterium than normal, non-labeled macitentan. Deuterium is a stable, non-radioactive isotope of hydrogen that is commonly used in pharmaceuticals as a tracer or a stabilizing agent. Macitentan D4 has the same chemical structure and mechanism of action as macitentan, but its deuterium content may affect its pharmacokinetics, or how the drug is absorbed, distributed, metabolized, and eliminated in the body.
In conclusion, Macitentan D4 is a medication used to treat pulmonary arterial hypertension by blocking the action of endothelin. It is administered orally and has the same chemical structure and mechanism of action as macitentan, but with a higher proportion of deuterium. It is important to follow the dosage instructions provided by the healthcare provider and to not exceed the recommended dose.
