Smiles
O=C(N(C1=CC=C(N(CCCC2)C2=O)C=C1)CC3)C4=C3C(C(OCC)=O)=NN4C5=CC=C(OC)C=C5
Therapeutic Uses
Anti-Thrombotics
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
Synonyms
ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
Application Notes
Impurity in commercial preparation of Apixaban.
Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);
Hazard Compound
Refer MSDS for accurate information
Impurity in commercial preparation of Apixaban.
Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
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Apixaban Ester Impurity usage and description
Apixaban is a widely used anticoagulant medication that is used to prevent blood clots and reduce the risk of stroke in people with certain medical conditions. However, during the manufacturing process of Apixaban, an impurity known as Apixaban Ester Impurity may be present. This impurity is a byproduct of the chemical synthesis process used to produce Apixaban.
The chemical structure of Apixaban Ester Impurity is similar to that of Apixaban, but it contains an additional ester group. This compound is classified as a potential impurity because it has the potential to affect the safety and efficacy of the final product. Therefore, it is important to monitor and control the levels of Apixaban Ester Impurity during the production process to ensure the safety and quality of the final product.
Toxicity studies conducted on Apixaban Ester Impurity indicate that it has a low toxicity profile, and it does not pose any significant health risks to humans. However, it is important to note that this compound is not intended for human consumption and should only be used for research and analytical purposes.
In conclusion, Apixaban Ester Impurity is a byproduct of the chemical synthesis process used to produce Apixaban. It is classified as a potential impurity and is important to monitor and control its levels during the production process to ensure the safety and quality of the final product. While it has a low toxicity profile, it should only be used for research and analytical purposes and not for human consumption.
