Therapeutic Uses
Anti-Hypertensives
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Trityl Losartan; [2-Butyl-5-chloro-3-[[2′-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-3H-imidazol-4-yl]methanol
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Losartan N1-Trityl Impurity is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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material handover.
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Losartan N1-Trityl Impurity usage and description
Losartan N1-Trityl Impurity is a chemical compound that is used in the synthesis of Losartan, a medication that is used to treat hypertension and other cardiovascular disorders. The impurity is a byproduct of the chemical reaction that is used to produce Losartan, and it is important to monitor the levels of the impurity in the drug product to ensure its safety and efficacy.
Chemically, Losartan N1-Trityl Impurity is a trityl-protected amino acid that is formed during the synthesis of Losartan. The trityl group is a benzyl protecting group that is used to protect the amino group during the synthesis. The impurity is typically removed during the purification process, but trace amounts may remain in the final drug product.
The presence of Losartan N1-Trityl Impurity in the final drug product can potentially affect its safety and efficacy. Therefore, regulatory agencies such as the FDA have set limits on the allowable levels of the impurity in Losartan products. Manufacturers of Losartan must ensure that the levels of this impurity are within acceptable limits before the drug is released to the market.
In conclusion, Losartan N1-Trityl Impurity is an important chemical compound that is closely monitored during the production of Losartan. Its presence in the final drug product can affect its safety and efficacy, and manufacturers must ensure that its levels are within acceptable limits before releasing the drug to the market.