Product Detail
Rilpivirine N-oxide
Rilpivirine Metabolite
Stock Status: In Stock
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For Research & Analytical Purposes. Not for Personal use.
Category
Metabolite
API Family
Rilpivirine
Storage
2-8°C
Hazard Information
Refer MSDS for complete information.
Rilpivirine N-oxide Product Information
Rilpivirine N-oxide is listed under Metabolite. It is associated with Rilpivirine and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-O-15496.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
Rilpivirine N-oxide
CAS No.
2734549-19-8
CAT No.
CS-O-15496
Molecular Formula
C22H18N6O
Molecular Weight
382.4
Category
API Family
Storage Condition
2-8°C
SMILES
CC1=CC(/C=C/C#N)=CC(C)=C1NC2=CC=[N+]([O-])C(NC3=CC=C(C#N)C=C3)=N2
IUPAC Name
(E)-2-((4-cyanophenyl)amino)-4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidine 1-oxide
Purity by HPLC
>98%
Hazard Compound
Refer MSDS for complete information.
Description
Overview
"Rilpivirine N1-Oxide is an impurity of Rilpivirine (R509800), a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. Rilpivirine is an anti-HIV agent."
Synonyms
(E)-2-((4-cyanophenyl)amino)-4-((4-(2-cyanovinyl)-2,6-dimethylphenyl)amino)pyrimidine 1-oxide
Application Notes
"Rilpivirine N1-Oxide is an impurity of Rilpivirine (R509800), a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. Rilpivirine is an anti-HIV agent."
References
"Sun, et al,: J, Med, Chem,, 41, 4648 (1998), Kashiwada, et al,: Bioorg, Med, Chem, Lett,, 11, 183 (2001),"
