CAS No.
[107868-30-4(Unlabeled)]
Therapeutic Uses
Anti-Cancer / Oncology
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
6-Methyleneandrosta-1,4-diene-3,17-dione (ACI); Aromasil
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Exemestane-d4 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Exemestane-d4 usage and description
Exemestane D4 is a deuterated form of the drug Exemestane, which is an aromatase inhibitor used in the treatment of breast cancer. Aromatase inhibitors work by blocking the enzyme aromatase, which is responsible for the conversion of androgens to estrogens in the body. Exemestane D4 is useful in clinical research as a stable isotope-labeled internal standard for quantitative analysis of Exemestane in biological fluids.
The chemical formula for Exemestane D4 is C20H14D4O2S, and its molecular weight is 318.48 g/mol. The deuterium-labeled compound is a white to off-white crystalline powder with a purity of at least 98% by HPLC. It is soluble in ethanol, methanol, and DMSO, but insoluble in water.
In terms of usage, Exemestane D4 is typically used in clinical research to evaluate the pharmacokinetics and metabolism of Exemestane in the body. It is often used in conjunction with liquid chromatography-mass spectrometry (LC-MS) to accurately measure the concentration of Exemestane in biological fluids such as plasma, serum, and urine.
Overall, Exemestane D4 is an important tool in the study of Exemestane and its effects on breast cancer treatment. Its stable isotope labeling gives it distinct advantages over non-labeled compounds, making it an ideal choice for use in quantitative analysis.
