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Home -- Sacubitril CS-O-16369

Sacubitrilat-d4

Explore technical data, documentation access, molecular information and enquiry options for this Clearsynth research product.

Product Code: CS-O-16369 -- Research Use Only
Sacubitrilat-d4
Category
--
API Family
Sacubitril
Product Code
CS-O-16369
Research Status
For Laboratory Use

Sacubitrilat-d4

Sacubitril --
Stock Status: In Stock
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CAT No.
CS-O-16369
CAS No.
149709-44-4(Unlabeled)
Molecular Formula
C₂₂H₂₁D₄NO₅
Molecular Weight
387.46
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal or Veterinary use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
149709-44-4(Unlabeled)
Product Code
CS-O-16369
M.F.
C₂₂H₂₁D₄NO₅
M.W.
387.46
API Family
Sacubitril
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
(2R,4S)-4-[(3-carboxy-2,2,3,3-tetradeuteriopropanoyl)amino]-2-methyl-5-(4-phenylphenyl)pentanoic acid
References
"McMurray, J,, et al,: N, Eng, J, Med,, 371 (2014);"
Synonyms
Not available,
Application Notes
"Sacubitrilat D4 is the labelled, deuterated version of Sacubitrilatl which is an impurity in the synthesis of Sacubitril, an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure."
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for accurate information.
Overview
"Sacubitrilat D4 is the labelled, deuterated version of Sacubitrilatl which is an impurity in the synthesis of Sacubitril, an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure."

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