Product Detail
Sacubitrilat-d4
Sacubitril Stable Isotopes
Stock Status: In Stock
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For Research & Analytical Purposes. Not for Personal use.
Category
Stable Isotopes
API Family
Sacubitril
Storage
Store at refrigerator (2-8°C) for long term storage
Hazard Information
Refer MSDS for accurate information.
Sacubitrilat-d4 Product Information
Sacubitrilat-d4 is listed under Stable Isotopes. It is associated with Sacubitril and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-O-16369.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
Sacubitrilat-d4
CAS No.
149709-44-4(Unlabeled)
CAT No.
CS-O-16369
Molecular Formula
C₂₂H₂₁D₄NO₅
Molecular Weight
387.46
Category
API Family
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoic acid-D4
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for accurate information.
Description
Overview
"Sacubitrilat D4 is the labelled, deuterated version of Sacubitrilatl which is an impurity in the synthesis of Sacubitril, an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure."
Synonyms
Not available,
Application Notes
"Sacubitrilat D4 is the labelled, deuterated version of Sacubitrilatl which is an impurity in the synthesis of Sacubitril, an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure."
References
"McMurray, J,, et al,: N, Eng, J, Med,, 371 (2014);"
