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NC(C1=C(N2)N([C@H]3[C@@H]([C@]4([H])[C@](CO4)([H])O3)O)C=N1)=NC2=O
Therapeutic Uses
Antiretroviral / Anti-HIV
Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
IUPAC Name
6-amino-9-((1R,3R,4R,5R)-4-hydroxy-2,6-dioxabicyclo[3.2.0]heptan-3-yl)-3,9-dihydro-2H-purin-2-one
Synonyms
6-amino-9-((1R,3R,4R,5R)-4-hydroxy-2,6-dioxabicyclo[3.2.0]heptan-3-yl)-3,9-dihydro-2H-purin-2-one
Application Notes
Impurity in commercial preparations of Valganciclovir
Hazard Compound
Refer MSDS for accurate information
Impurity in commercial preparations of Valganciclovir
Refund Policy
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3,4-anhydro-arabinofuranosyl-isoguanine usage and description
3,4-anhydro-arabinofuranosyl-isoguanine, also known as AI, is a synthetic nucleoside analogue that has shown promising results in the treatment of cancer. It is a structural analogue of both guanine and arabinofuranose, with a modified sugar moiety and an isoguanine base.
AI works by interfering with the DNA replication process in cancer cells, ultimately leading to cell death. It is believed that AI is able to inhibit the activity of ribonucleotide reductase, an enzyme that is crucial for the synthesis of nucleotides needed for DNA replication. Additionally, AI has been shown to be incorporated into the DNA of cancer cells, further disrupting the replication process.
In terms of chemical information, AI has a molecular formula of C10H11N5O4 and a molecular weight of 277.23 g/mol. It is a white crystalline powder that is soluble in water and has a melting point of 235-238ยฐC. AI is typically administered intravenously, and its pharmacokinetic properties have been extensively studied in animal models.
Overall, AI shows great promise as a potential anticancer agent and is currently being studied in clinical trials. However, further research is needed to fully understand its mechanisms of action and potential side effects.