API Product Detail

Ivosidenib

Name: Ivosidenib
Brand: Clearsynth
SKU: CS-O-16987
Availability: LimitedAvailability

Chemical Properties and Information

Product Code: CS-O-16987 API

API Family

Ivosidenib

Product Code

CS-O-16987

Ivosidenib

Ivosidenib API

Stock Status: : Enquire Live

CAT No.

CS-O-16987

CAS No.

1448347-49-6

Molecular Formula

C₂₈H₂₂ClF₃N₆O₃

Molecular Weight

583

There is no hazardous surcharge associated with this product.

There is no packaging charge associated with this product.

For Research Purposes only. Not for Personal use.

All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.

CAS No.

1448347-49-6

Product Code

CS-O-16987

M.F.

C₂₈H₂₂ClF₃N₆O₃

M.W.

583

Smiles

O=C([C@H](CC1)N(C2=CC(C#N)=CC=N2)C1=O)N([C@@H](C(C=CC=C3)=C3Cl)C(NC4CC(F)(F)C4)=O)C5=CN=CC(F)=C5

Category

API

API Family

Ivosidenib

Storage Condition

2-8 degree

IUPAC Name

"(S)-N-((S)-1-(2-Chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide"

References

Caino MC, Altieri DC. Molecular Pathways: Mitochondrial Reprogramming in Tumor Progression and Therapy. Clin Cancer Res. 2016 Feb 1;22(3):540-5. doi: 10.1158/1078-0432.CCR-15-0460. Review. PubMed PMID: 26660517; PubMed Central PMCID: PMC4738153. Chen J, Yang J, Cao P. The Evolving Landscape in the Development of Isocitrate Dehydrogenase Mutant Inhibitors. Mini Rev Med Chem. 2016;16(16):1344-1358. PubMed PMID: 27292784.

Synonyms

1448346-63-1; Ivosidenib, AG-120; AG120; AG 120; RG-120; RG 120; RG120; (S)-N-((S)-1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide

Application Notes

Useful research chemical for a range of applications

Hazard Compound

Refer MSDS for complete information.

Overview

Useful research chemical for a range of applications