N-Desmethyl Netupitant-d6

2070015-21-1

CS-O-20023

C₂₉H₂₄D₆F₆N₄O

570.60

O=C(N(C)C1=C(C2=CC=CC=C2C)C=C(N3CCNCC3)N=C1)C(C([2H])([2H])[2H])(C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C([2H])([2H])[2H]

Metabolite

Netupitant

Store at refrigerator (2-8°C) for long term storage

2-[3,5-bis(trifluoromethyl)phenyl]-3,3,3-trideuterio-N-methyl-N-[4-(2-methylphenyl)-6-piperazin-1-ylpyridin-3-yl]-2-(trideuteriomethyl)propanamide

"Hoffmann; T,; et al,: Bioorg, Med, Chem, Lett,; 16; 1362 (2006); Di Fabio; R,; et al,: Bioorg, Med, Chem,; 21; 6264 (2013)"

2-[3,5-bis(trifluoromethyl)phenyl]-3,3,3-trideuterio-N-methyl-N-[4-(2-methylphenyl)-6-piperazin-1-ylpyridin-3-yl]-2-(trideuteriomethyl)propanamide

"N-Desmethyl Netupitant-d6 is labelled N-Desmethyl Netupitant which is a derivative of Netupitant . Netupitant is a potent and selective neurokinin-1 receptor (NK1) receptor antagonist. Netupitant is achiral and orally active.;Labeled Netupitant, intended for use as an internal standard for the quantification of Netupitant by GC- or LC-mass spectrometry."

99.17

Refer MSDS for complete information.