Therapeutic Uses
Anti-Migraines
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Nadolol-d9, 94513-92-5
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90 %
Hazard Compound
No -Refer MSDS for accurate information
Nadolol-d9 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
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Nadolol-d9 usage and description
Nadolol D9 is a deuterated form of the beta-adrenergic blocker, nadolol. The deuterium substitution in Nadolol D9 involves the replacement of nine of the hydrogen atoms in the molecule with deuterium atoms. This isotopic substitution increases the molecular weight of Nadolol D9 and alters its chemical properties, resulting in a longer half-life and improved bioavailability.
Nadolol D9 is commonly used in the treatment of hypertension, angina, and arrhythmias. It works by blocking the action of epinephrine and norepinephrine, which are hormones that increase heart rate and blood pressure. By blocking these hormones, Nadolol D9 reduces heart rate and blood pressure, thereby decreasing the workload on the heart and improving cardiac function.
Chemically, Nadolol D9 is a white crystalline powder that is soluble in water and ethanol. Its chemical formula is C17H18D9NO4, and its molecular weight is 298.42 g/mol. The deuterium substitution in Nadolol D9 increases its mass by 9 atomic mass units, which can affect its metabolism and pharmacokinetics. The half-life of Nadolol D9 is approximately 24 hours, which is longer than the half-life of non-deuterated nadolol.
In conclusion, Nadolol D9 is an effective beta-adrenergic blocker that is used in the treatment of hypertension, angina, and arrhythmias. Its deuterium substitution improves its pharmacokinetics, resulting in a longer half-life and improved bioavailability.
