CAS No.
[174264-50-7(Unlabeled)]
Smiles
O=C([C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC2=CC=C(C(C(C3=CC=C(OC([2H])([2H])C([2H])([2H])N4CCCCC4)C=C3)=O)=C(C5=CC=C(O)C=C5)S6)C6=C2)O1)O
Therapeutic Uses
Anti-Cancer / Oncology
Storage Condition
Refer MSDS for complete information
IUPAC Name
(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-((2-(4-hydroxyphenyl)-3-(4-(2-(piperidin-1-yl)ethoxy(D4))benzoyl)benzo[b]thiophen-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
Synonyms
(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-((2-(4-hydroxyphenyl)-3-(4-(2-(piperidin-1-yl)ethoxy(D4))benzoyl)benzo[b]thiophen-6-yl)oxy)tetrahydro-2H-pyran-2-carboxylic acid
Application Notes
"Labeled glucuronide of Raloxifene, intended for use as an internal standard for the quantification of Raloxifene by GC- or LC-mass spectrometry."
Hazard Compound
No -Refer MSDS for accurate information
Raloxifene-d4 6-Glucuronide is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Raloxifene-d4 6-Glucuronide usage and description
Raloxifene-d4 6-Glucuronide is a deuterated form of Raloxifene 6-Glucuronide, which is a metabolite of Raloxifene. Raloxifene is a selective estrogen receptor modulator (SERM) used in the treatment of osteoporosis in postmenopausal women. Raloxifene-d4 6-Glucuronide is used as a reference standard in the development of analytical methods for the quantification of Raloxifene 6-Glucuronide in biological samples.
Chemically, Raloxifene-d4 6-Glucuronide is a glucuronide conjugate of Raloxifene, which is formed in the liver and excreted in the bile. It is a white to off-white powder with a molecular weight of 587.59 g/mol. It is soluble in water and ethanol.
In terms of usage, Raloxifene-d4 6-Glucuronide is primarily used in the development of analytical methods for the quantification of Raloxifene 6-Glucuronide in biological samples. It is also used as a reference standard in pharmacokinetic studies of Raloxifene and its metabolites. The compound is typically used in conjunction with high-performance liquid chromatography (HPLC) or mass spectrometry (MS) techniques for the analysis of biological samples.
In conclusion, Raloxifene-d4 6-Glucuronide is an important reference standard in the development of analytical methods for the quantification of Raloxifene 6-Glucuronide in biological samples. Its chemical properties and solubility make it a useful tool in pharmacokinetic studies of Raloxifene and its metabolites.