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Bortezomib 1R, 2R Isomer

Chemical Properties and Information

Product Code: CS-O-31035 Chiral
Bortezomib 1R, 2R Isomer
API Family
Bortezomib
Product Code
CS-O-31035

Bortezomib 1R, 2R Isomer

Bortezomib Chiral
Stock Status: In Stock
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CAT No.
CS-O-31035
CAS No.
1132709-15-9
Molecular Formula
C19H25BN4O4
Molecular Weight
384.2
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
1132709-15-9
Product Code
CS-O-31035
M.F.
C19H25BN4O4
M.W.
384.2
Smiles
CC(C)C[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)c2cnccn2)B(O)O
Category
Chiral
API Family
Bortezomib
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
((R)-3-Methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid
References
"Nawrocki, S,T,, et al: Cancer Research, 65, 11510 (2005); Drahl C,: Chem, and Eng, News, 87, 41 (2009)"
Synonyms
"Bortezomib Impurity (R,R-Isomer)"
Application Notes
" (1R,2R)-Bortezomib is a diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway"
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for accurate information.
Overview
" (1R,2R)-Bortezomib is a diastereomer of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway"
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