Smiles
N#CC1=CC=CC=C1CN(C(N2C)=O)C(Cl)=CC2=O
Therapeutic Uses
Anti-Diabetic
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-benzonitrile
Synonyms
Alogliptin 6-Chloro Impurity
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Alogliptin 6-Chloro Impurity is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Alogliptin 6-Chloro Impurity usage and description
Alogliptin impurity B is a chemical compound that is commonly used in the pharmaceutical industry as an intermediate or a starting material for the synthesis of alogliptin, a medication used in the treatment of type 2 diabetes mellitus. This impurity is also known as (2S,4S)-4-aminopiperidine-2-carboxylic acid and has a molecular formula of C6H12N2O2.
In terms of chemical information, alogliptin impurity B is a piperidine derivative that contains a carboxylic acid group and an amino group. It has a melting point range of 224-227 °C and a solubility of 0.3 g/L in water at 25 °C. The compound is stable under normal conditions and does not pose a significant safety risk.
The usage of alogliptin impurity B is mainly restricted to the pharmaceutical industry where it is used as a starting material for the synthesis of alogliptin. The impurity is added to the reaction mixture and undergoes a series of chemical reactions to form the final product. Alogliptin is an oral hypoglycemic agent that works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4), which is responsible for the breakdown of incretin hormones. By inhibiting DPP-4, alogliptin increases the release of insulin and decreases the release of glucagon, leading to improved glycemic control in patients with type 2 diabetes mellitus.
Overall, alogliptin impurity B plays a crucial role in the synthesis of alogliptin, which is an important medication used in the management of type 2 diabetes mellitus.
