CAS No.
[1231930-25-8 (Unlabeled)]
Therapeutic Uses
Anti-Cancer / Oncology
Storage Condition
Refer MSDS for complete information
Synonyms
1-((6-bromopyridin-3-yl)methyl)-4-ethyl-d5-piperazine
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Abemaciclib Impurity 5-d5 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Abemaciclib Impurity 5-d5 usage and description
Abemaciclib Impurity 5 D5 is a chemical compound that is used in the development and testing of pharmaceutical products. It is a stable isotope of Abemaciclib Impurity 5, a known impurity in the synthesis of Abemaciclib, which is a kinase inhibitor used in the treatment of breast cancer.
Abemaciclib Impurity 5 D5 is used as a reference standard in analytical methods to quantify the amount of Abemaciclib Impurity 5 in pharmaceutical formulations. This compound is also used in pharmacokinetic studies to determine the metabolism and clearance of Abemaciclib Impurity 5 in vivo.
The chemical formula of Abemaciclib Impurity 5 D5 is C22H13D5N6O2, and it has a molecular weight of 409.47 g/mol. This compound is a labeled analogue of Abemaciclib Impurity 5, with five deuterium atoms incorporated into the molecule.
The incorporation of deuterium into Abemaciclib Impurity 5 D5 provides several advantages in drug development. Deuterium is a stable isotope of hydrogen, and its incorporation into drug molecules can increase their metabolic stability, reduce toxicity, and enhance drug efficacy.
In conclusion, Abemaciclib Impurity 5 D5 is a valuable tool in drug development and testing, as it provides important chemical and pharmacokinetic information that is essential for the development of safe and effective pharmaceutical products.
