CAS No.
[220991-32-2 (unlabeled)]
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Robenacoxib-d5, 220991-32-2 (unlabeled)
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Robenacoxib-d5 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Robenacoxib-d5 usage and description
Robenacoxib-d5 is a deuterated form of the nonsteroidal anti-inflammatory drug (NSAID), robenacoxib. It is commonly used in veterinary medicine for the treatment of pain and inflammation associated with osteoarthritis and postoperative pain in dogs and cats.
Chemically, robenacoxib-d5 is a selective inhibitor of cyclooxygenase-2 (COX-2), an enzyme involved in the production of prostaglandins that cause pain and inflammation. By inhibiting COX-2, robenacoxib-d5 reduces pain and inflammation without affecting the production of prostaglandins involved in normal physiological processes.
Robenacoxib-d5 is administered orally in tablet form and is rapidly absorbed into the bloodstream, with peak plasma concentrations reached within 1-2 hours. It has a half-life of approximately 4 hours in dogs and 2.5 hours in cats.
As with all NSAIDs, robenacoxib-d5 carries a risk of adverse effects, particularly gastrointestinal ulceration and bleeding, as well as renal and hepatic toxicity. It should not be used in animals with a history of sensitivity to NSAIDs, or those with pre-existing renal or hepatic disease. Careful monitoring is recommended during treatment with robenacoxib-d5, and it should only be used under the guidance of a licensed veterinarian.
