CAS No.
[119717-21-4 (Unlabeled)]
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Levomedetomidine-d8 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Levomedetomidine-d8 usage and description
Levomedetomidine d8 is a synthetic analogue of medetomidine, a potent alpha-2 adrenergic receptor agonist used in veterinary medicine for sedation and analgesia. Levomedetomidine d8 is a deuterated version of this compound, where eight hydrogen atoms have been replaced with deuterium atoms. This modification provides several advantages, including increased stability and improved pharmacokinetic properties.
Levomedetomidine d8 is primarily used in preclinical research as a tracer for studying the pharmacokinetics and metabolism of medetomidine in vivo. It is also used in drug metabolism studies to evaluate the pharmacokinetics, bioavailability, and clearance of medetomidine and other alpha-2 adrenergic receptor agonists.
Chemically, Levomedetomidine d8 is a clear, colorless liquid that is stable under normal conditions. It has a molecular weight of 224.43 g/mol and a chemical formula of C14H16D8N3. The compound is typically administered intravenously or intramuscularly, and its effects last for several hours.
Overall, Levomedetomidine d8 is a valuable tool for preclinical researchers studying the pharmacokinetics and metabolism of medetomidine and related compounds. Its deuterated structure provides improved stability and pharmacokinetic properties, making it an ideal tracer for use in animal studies.
