Storage Condition
Refer MSDS for complete information
Synonyms
Erlotinib 7-O-Desmethyl Metabolite; Erlotinib Metabolite M13 ; 2-((4-((3-ethynylphenyl)amino)-6-(2-methoxyethoxy)quinazolin-7-yl)oxy)ethanol formate; 7-O-Desmethyl Erlotinib Formate
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
7-(2’-Desmethyl) Erlotinib formate salt is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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7-(2’-Desmethyl) Erlotinib formate salt usage and description
7-(2’-Desmethyl) Erlotinib formate salt is a chemical compound that is used in the treatment of non-small cell lung cancer (NSCLC). It is a derivative of Erlotinib, a tyrosine kinase inhibitor that works by blocking the action of an enzyme called epidermal growth factor receptor (EGFR), which is involved in the growth and spread of cancer cells. The 7-(2’-Desmethyl) Erlotinib formate salt is a salt of the active metabolite of Erlotinib, which has been shown to have improved pharmacokinetic properties and increased potency compared to the parent compound.
The chemical formula of 7-(2’-Desmethyl) Erlotinib formate salt is C22H23N3O4.HCOOH, and its molecular weight is 429.45 g/mol. It is a white to off-white crystalline powder that is soluble in water and organic solvents such as ethanol and methanol. Its melting point is around 200-205°C.
7-(2’-Desmethyl) Erlotinib formate salt is typically administered orally in the form of tablets or capsules. The recommended dose and duration of treatment depend on various factors such as the patient's age, weight, and overall health, as well as the type and stage of cancer being treated. Adverse effects of this drug may include diarrhea, skin rash, and fatigue, among others.
In summary, 7-(2’-Desmethyl) Erlotinib formate salt is a potent and effective drug used in the treatment of NSCLC. Its chemical properties and pharmacokinetics make it an attractive option for cancer therapy, and ongoing research is being conducted to explore its potential in other types of cancer.
