M.F.
CโโHโโDโNโOโS
Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
(S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide-2,2,2-d3
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Apremilast-d3 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
always, we appreciate your support.
Apremilast-d3 usage and description
Apremilast D3 is a chemical compound used in the treatment of psoriasis and psoriatic arthritis. It is a derivative of Apremilast, which is an inhibitor of phosphodiesterase 4 (PDE4) enzyme. Apremilast D3 is a stable isotope-labeled compound of Apremilast that can be used in various research applications, such as pharmacokinetic studies, metabolic labeling, and drug discovery.
The chemical formula of Apremilast D3 is C22H17D3N2O7PS, and its molecular weight is 500.50 g/mol. The compound is a white to off-white powder that is soluble in dimethyl sulfoxide (DMSO) and dimethylformamide (DMF). It is stable under normal storage conditions and can be stored at -20ยฐC.
Apremilast D3 works by inhibiting the PDE4 enzyme, which is responsible for the degradation of cyclic adenosine monophosphate (cAMP). By inhibiting PDE4, Apremilast D3 increases the level of cAMP in cells, which leads to the suppression of inflammatory cytokines and chemokines. This mechanism of action makes Apremilast D3 effective in the treatment of psoriasis and psoriatic arthritis, which are inflammatory conditions.
In conclusion, Apremilast D3 is a stable isotope-labeled compound of Apremilast that is used in various research applications. It works by inhibiting the PDE4 enzyme and increasing the level of cAMP in cells, which leads to the suppression of inflammatory cytokines and chemokines. Apremilast D3 is an important tool for researchers studying the pharmacokinetics and mechanism of action of Apremilast and its derivatives.