Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
(S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide-2,2,2-d3
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Apremilast-d3 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Apremilast-d3 usage and description
Apremilast D3 is a chemical compound used in the treatment of psoriasis and psoriatic arthritis. It is a derivative of Apremilast, which is an inhibitor of phosphodiesterase 4 (PDE4) enzyme. Apremilast D3 is a stable isotope-labeled compound of Apremilast that can be used in various research applications, such as pharmacokinetic studies, metabolic labeling, and drug discovery.
The chemical formula of Apremilast D3 is C22H17D3N2O7PS, and its molecular weight is 500.50 g/mol. The compound is a white to off-white powder that is soluble in dimethyl sulfoxide (DMSO) and dimethylformamide (DMF). It is stable under normal storage conditions and can be stored at -20°C.
Apremilast D3 works by inhibiting the PDE4 enzyme, which is responsible for the degradation of cyclic adenosine monophosphate (cAMP). By inhibiting PDE4, Apremilast D3 increases the level of cAMP in cells, which leads to the suppression of inflammatory cytokines and chemokines. This mechanism of action makes Apremilast D3 effective in the treatment of psoriasis and psoriatic arthritis, which are inflammatory conditions.
In conclusion, Apremilast D3 is a stable isotope-labeled compound of Apremilast that is used in various research applications. It works by inhibiting the PDE4 enzyme and increasing the level of cAMP in cells, which leads to the suppression of inflammatory cytokines and chemokines. Apremilast D3 is an important tool for researchers studying the pharmacokinetics and mechanism of action of Apremilast and its derivatives.
