Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
N,N-Bis(butyl-d9)nitrous amide; N-Butyl-N-nitroso-1-butanamine-d18; Nitrosodibutylamine-d18
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
N-Nitroso-Di-N-Butylamine (d18, 98%) 1mg/ml in Methylene Chloride-d2 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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N-Nitroso-Di-N-Butylamine (d18, 98%) 1mg/ml in Methylene Chloride-d2 usage and description
N-Nitroso-Di-N-Butylamine, also known as D18, is a highly toxic, carcinogenic chemical compound that belongs to the family of nitrosamines. It is commonly used in chemical research and industrial applications, particularly in the production of rubber, pesticides, and pharmaceuticals. This compound is highly unstable and reacts easily with other chemicals, making it a dangerous substance to handle.
D18 is typically prepared as a 1 mg/mL solution in methylene chloride-d2, which is a deuterated solvent that is commonly used in nuclear magnetic resonance (NMR) spectroscopy. This solution is used in NMR experiments to study the structure and properties of D18 and other nitrosamines. The use of deuterated solvents is important in NMR spectroscopy because it helps to minimize the interference caused by the solvent signals, which can obscure the signals of interest.
The chemical structure of D18 consists of a nitroso group (NO) attached to a di-n-butylamine molecule. The nitroso group is highly reactive and can form covalent bonds with other molecules, leading to the formation of DNA adducts and other mutagenic and carcinogenic compounds. Due to its carcinogenic properties, D18 is classified as a Group 1 carcinogen by the International Agency for Research on Cancer (IARC). As such, strict safety precautions must be taken when handling this compound.