Storage Condition
Refer MSDS for complete information
Synonyms
dimethyl ((2S,2'S)-((2S,2'S)-2,2'-(5,5'-([1,1'-biphenyl]-4,4'-diyl)bis(1-nitroso-1H-imidazole-5,2-diyl))bis(pyrrolidine-2,1-diyl))bis(3-methyl-1-oxobutane-2,1-diyl))dicarbamate
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Daclatasvir dihydrochloride nitrosamine impurity is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
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Daclatasvir dihydrochloride nitrosamine impurity usage and description
Daclatasvir dihydrochloride is a medication used to treat chronic hepatitis C virus (HCV) infection. It works by inhibiting the HCV nonstructural protein 5A (NS5A), which is necessary for viral replication. However, during the manufacturing process of Daclatasvir dihydrochloride, a nitrosamine impurity can form. Nitrosamines are a class of compounds that have been shown to be carcinogenic in animal studies. The nitrosamine impurity in Daclatasvir dihydrochloride has been identified as N-nitrosodimethylamine (NDMA).
NDMA is a highly toxic and carcinogenic compound that has been classified as a probable human carcinogen by the International Agency for Research on Cancer (IARC). Exposure to NDMA can cause damage to the liver, kidneys, and other organs. Therefore, it is essential to monitor and control the levels of NDMA in Daclatasvir dihydrochloride to ensure that the medication is safe for use.
To avoid exposure to NDMA, it is important to follow the recommended dosage and administration of Daclatasvir dihydrochloride and to only use the medication as prescribed by a healthcare professional. Patients should also be aware of any potential side effects and report them to their healthcare provider immediately. It is also recommended that patients undergo regular liver function tests while taking Daclatasvir dihydrochloride to monitor for any signs of liver damage.
