Storage Condition
Refer MSDS for complete information
Synonyms
(R)-4-((2-(5-(2-fluoro-3-hydroxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoic acid
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
O-Demethyl elagolix is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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O-Demethyl elagolix usage and description
O-Demethyl elagolix is a synthetic peptide that is commonly used in the treatment of endometriosis and uterine fibroids. It works by selectively blocking the gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland, which leads to a decrease in the production of estrogen and progesterone hormones. This, in turn, reduces the size and symptoms of the aforementioned conditions.
The chemical formula of O-Demethyl elagolix is C29H28F3N3O3, and its molecular weight is 535.55 g/mol. It is a white to off-white powder that is insoluble in water but soluble in organic solvents such as dimethyl sulfoxide (DMSO) and methanol.
O-Demethyl elagolix is a metabolite of the drug elagolix, which is also used for the same conditions. However, O-Demethyl elagolix has a shorter half-life and is eliminated from the body faster than its parent drug.
The recommended dosage of O-Demethyl elagolix varies depending on the condition being treated, but it is typically taken orally once or twice daily. Side effects may include hot flashes, headaches, nausea, and mood changes.
In conclusion, O-Demethyl elagolix is a useful medication for managing endometriosis and uterine fibroids. Its selective blocking of GnRH receptors leads to a decrease in estrogen and progesterone levels, which helps alleviate symptoms. However, as with any medication, it is essential to consult with a healthcare provider before taking O-Demethyl elagolix.