Semaglutide Iso Asp Impurity

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CS-O-45106

C₁₈₇H₂₉₁N₄₅O₅₉

4113.64

O=C(O)CCCCCCCCCCCCCCCCC(N[C@@H](C(O)=O)CCC(NCCOCCOCC(NCCOCCOCC(NCCCC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(C[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(C(C)(C)NC([C@@H](N)CC1=CN=CN1)=O)=O)CCC(O)=O)=O)=O)[C@H](O)C)=O)CC2=CC=CC=C2)=O)[C@H](O)C)=O)CO)=O)C(O)=O)=O)C(C)C)=O)CO)=O)CO)=O)CC3=CC=C(O)C=C3)=O)CC(C)C)=O)CCC(O)=O)=O)=O)CCC(N)=O)=O)C)=O)C)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N[C@@H](CC5=CNC6=C5C=CC=C6)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCNC(N)=N)C(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Impurity

Semaglutide

Store at refrigerator (2-8°C) for long term storage

(3S,9S,12S,15S,18S,21S,25S,28S,31S,34S,37S,40S,46S,49S,52S,55S,82R)-55-(((6S,12S,15S,18S,21S,24S,27S,30S,33S)-21-((1H-indol-3-yl)methyl)-1-amino-30-benzyl-27-((S)-sec-butyl)-35-carboxy-6-((carboxymethyl)carbamoyl)-12-(3-guanidinopropyl)-1-imino-18-isobutyl-15-isopropyl-24-methyl-8,11,14,17,20,23,26,29,32-nonaoxo-2,7,10,13,16,19,22,25,28,31-decaazapentatriacontan-33-yl)carbamoyl)-3-(2-((S)-2-amino-3-(1H-imidazol-5-yl)propanamido)-2-methylpropanamido)-46-(3-amino-3-oxopropyl)-12-benzyl-40-(2-carboxyethyl)-34-(4-hydroxybenzyl)-9,15-bis((R)-1-hydroxyethyl)-18,28,31-tris(hydroxymethyl)-37-isobutyl-25-isopropyl-49,52-dimethyl-4,7,10,13,16,19,23,26,29,32,35,38,41,44,47,50,53,61,70,79,84-henicosaoxo-63,66,72,75-tetraoxa-5,8,11,14,17,20,24,27,30,33,36,39,42,45,48,51,54,60,69,78,83-henicosaazahectane-1,21,82,100-tetracarboxylic acid

CAS
PubChem
Wikipedia

L-Histidylaminoisobutyryl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-isoaspartyl-Lvalyl-L-Seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N-6-[18-[N-(17-carboxyheptadecanoyl)-L-gamma-glutamyl]-10-oxo-3,6,12,15-tetraoxa-9,18-diazactadecanoyl]-L-lysyl-L-alpha-glutamyl-Lphenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine

Semaglutide Iso Asp Impurity

Refer MSDS for accurate information.