CAS No.
[2892260-32-9 (Unlabelled)]
Storage Condition
Refer MSDS for complete information
Synonyms
7-nitroso-3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-6,6,8,8-d4
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Nitroso-STG-19 (Sitagliptin)-6,6,8,8-d4 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Nitroso-STG-19 (Sitagliptin)-6,6,8,8-d4 usage and description
Nitroso-STG-19 (Sitagliptin)-6,6,8,8-d4 is a stable isotope-labeled version of Sitagliptin, a medication used to treat type 2 diabetes. It is a dipeptidyl peptidase-4 (DPP-4) inhibitor that works by increasing the levels of incretin hormones in the body, which help regulate blood sugar levels. Nitroso-STG-19 (Sitagliptin)-6,6,8,8-d4 has the same mechanism of action as Sitagliptin, but with the added benefit of being able to track the drug's metabolism and distribution within the body.
The chemical formula of Nitroso-STG-19 (Sitagliptin)-6,6,8,8-d4 is C16H12D4F6N5O2, and it has a molecular weight of 403.38 g/mol. It is a white or off-white crystalline powder with a melting point of 182-183°C.
Nitroso-STG-19 (Sitagliptin)-6,6,8,8-d4 is typically administered orally in tablet form, with a recommended dosage of 100 mg once daily. It is metabolized in the liver and excreted in the urine, with a half-life of approximately 12.4 hours.
As with any medication, Nitroso-STG-19 (Sitagliptin)-6,6,8,8-d4 may cause side effects such as nausea, headache, and joint pain. It is important to follow the recommended dosage and consult with a healthcare professional before taking this medication. Overall, Nitroso-STG-19 (Sitagliptin)-6,6,8,8-d4 is a useful tool in studying the pharmacokinetics and pharmacodynamics of Sitagliptin, and may lead to further advancements in the treatment of type 2 diabetes.