CAS No.
[1217770-29-0 (Unlabelled)]
Storage Condition
Refer MSDS for complete information
Synonyms
(R)-4-(2-((3-((9H-carbazol-4-yl)oxy)-2-hydroxypropyl)amino)ethoxy)-3-(methoxy-d3)phenol
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
(R)-4-Hydroxycarvedilol-D3 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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(R)-4-Hydroxycarvedilol-D3 usage and description
(R)-4-Hydroxycarvedilol-D3 is a deuterated form of the active metabolite of the ฮฒ-adrenoceptor antagonist drug, Carvedilol. The compound is used primarily in pharmacological research to track the fate and metabolism of Carvedilol within the human body.
Carvedilol is a non-selective ฮฒ-blocker that is used to treat hypertension, congestive heart failure, and angina. It works by blocking the effects of the hormone adrenaline, which reduces the workload of the heart and improves its function. The active metabolite of Carvedilol is (R)-4-Hydroxycarvedilol, which is formed in the liver through the process of oxidation.
(R)-4-Hydroxycarvedilol-D3 is a deuterated form of this metabolite, which means that it contains three deuterium atoms instead of three hydrogen atoms. This makes it useful for pharmacokinetic studies, as the deuterium atoms do not significantly alter the chemical properties of the compound but allow for tracking of its metabolism and clearance within the body.
Overall, (R)-4-Hydroxycarvedilol-D3 is an important tool in pharmacological research, as it provides valuable insight into the fate and effects of Carvedilol within the human body. Its chemical structure and properties make it a useful tracer compound that can be used in a variety of studies to better understand the pharmacokinetics and pharmacodynamics of Carvedilol and other related drugs.
