Therapeutic Uses
Anti-Cancer / Oncology
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
3-Deoxy 3-Chloro Abiraterone, 2484719-16-4
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
3-Deoxy 3-Chloro Abiraterone is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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3-Deoxy 3-Chloro Abiraterone usage and description
3-Deoxy 3-Chloro Abiraterone is a novel and potent inhibitor of CYP17A1, an enzyme involved in androgen biosynthesis. This compound is a derivative of Abiraterone, a drug used to treat prostate cancer, but with improved pharmacological properties. 3-Deoxy 3-Chloro Abiraterone has been shown to have superior activity compared to Abiraterone in preclinical studies.
The primary usage of 3-Deoxy 3-Chloro Abiraterone is in the treatment of prostate cancer. It works by inhibiting the production of androgens, which are hormones that promote the growth of prostate cancer cells. By reducing the levels of androgens in the body, this drug can slow the progression of prostate cancer and improve overall survival rates.
Chemically, 3-Deoxy 3-Chloro Abiraterone is a steroidal compound that contains a chlorine atom at the 3-position and lacks the hydroxyl group at the 3-position found in Abiraterone. This modification improves the potency and selectivity of the compound, making it more effective at inhibiting CYP17A1. Additionally, 3-Deoxy 3-Chloro Abiraterone has better pharmacokinetic properties than Abiraterone, with greater oral bioavailability and longer half-life.
In conclusion, 3-Deoxy 3-Chloro Abiraterone is a promising drug for the treatment of prostate cancer, with superior activity and improved pharmacological properties compared to Abiraterone. Its chemical structure and mechanism of action make it a valuable addition to the arsenal of drugs used to fight prostate cancer.
