Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
25-O-Desacetyl Rifabutin-d7, Not available
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
25-O-Desacetyl Rifabutin-d7 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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25-O-Desacetyl Rifabutin-d7 usage and description
25-O-Desacetyl Rifabutin-d7 is a deuterated derivative of the antibiotic drug Rifabutin, which is used to treat infections caused by Mycobacterium avium complex (MAC) in patients with acquired immunodeficiency syndrome (AIDS). The deuterated form of the drug is used in research and development to better understand the pharmacokinetics and metabolism of the original drug.
The chemical formula of 25-O-Desacetyl Rifabutin-d7 is C46H42D7N3O11 and it has a molecular weight of 862.95 g/mol. The drug is a semi-synthetic compound and has a similar chemical structure to rifamycin, a group of antibiotics that inhibit bacterial RNA polymerase.
The usage of 25-O-Desacetyl Rifabutin-d7 is mainly in pharmacokinetic studies to determine the drug's absorption, distribution, metabolism, and excretion in vivo. The deuterated form of Rifabutin is used as a tracer to differentiate the drug from other metabolites in a biological matrix. It is also used to investigate drug-drug interactions and the effects of food on drug absorption.
In conclusion, 25-O-Desacetyl Rifabutin-d7 is a deuterated derivative of the antibiotic drug Rifabutin, which is used in research to better understand the pharmacokinetics and metabolism of the drug. It is mainly used in pharmacokinetic studies to determine the drug's absorption, distribution, metabolism, and excretion in vivo.
