Storage Condition
Refer MSDS for complete information
Synonyms
2-(amino-15N)-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one-15N4; 15N5-2′-Deoxyguanosine
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
2-Deoxyguanosine-15N5 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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2-Deoxyguanosine-15N5 usage and description
2-Deoxyguanosine-15N5 is a stable isotope labeled compound that is primarily used in scientific research for various applications. It is a modified form of the naturally occurring nucleoside 2-deoxyguanosine, where five nitrogen atoms are replaced with stable isotopes of nitrogen-15. This labeling makes it an ideal compound for metabolic labeling studies, mass spectrometry-based proteomics, and biomolecular NMR spectroscopy.
2-Deoxyguanosine-15N5 is commonly used in the study of DNA replication, repair, and synthesis. It is also used in the study of DNA methylation and epigenetics. This compound is used as a precursor for the synthesis of DNA and RNA molecules that are labeled with stable isotopes of nitrogen-15. This labeling technique allows researchers to track the movement of molecules through metabolic pathways and determine the structure and function of biomolecules in living cells.
Chemically, 2-Deoxyguanosine-15N5 is a white crystalline powder that is soluble in water and other polar solvents. It has a molecular weight of 270.22 g/mol and a melting point of 234-236°C. It is stable under normal storage conditions and should be kept in a dry, cool place away from sources of light and heat. This compound is considered to be non-toxic and non-hazardous, but proper handling and disposal should be followed according to established laboratory protocols.
