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For Research Purposes only. Not for Personal use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
289472-80-6
Product Code
CS-P-07311
M.F.
C₁₄H₁₄N₄O₂
M.W.
270.29
Smiles
O=C(C1=NC=CN=C1)N[C@@H](CC2=CC=CC=C2)C(N)=O
Category
Impurity
API Family
Bortezomib
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Pekol, T., et al.: Drug. Meta. Disp., 33, 771 (2005); Hsieh, F.Y., et al.: J. Pharma. Biomed. Anal., 49, 115 (2009);
Synonyms
Bortezomib Amide Analog; Bortezomib Impurity A
Application Notes
N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide is a metabolite of Bortezomib (B675700), a proteasome inhibitor for the treatment of multiple myeloma and is known to also target the ubiquitin-proteasome pathway.
Purity by HPLC
99.80%
Hazard Compound
Refer MSDS for accurate information.
Overview
N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide is a metabolite of Bortezomib (B675700), a proteasome inhibitor for the treatment of multiple myeloma and is known to also target the ubiquitin-proteasome pathway.
![Pyrazine-2-carboxylic acid [1-(1-hydroxy-3-methyl-butyl carbamoyl)-2-phenyl-ethyl]-amide](https://structures.clearsynth.com/CS-O-36966.png)
![N,N-Bis(trimethylsilyl)-(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutylamine](https://structures.clearsynth.com/CS-O-37985.png)