Therapeutic Uses
Anti-Thrombotics
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
3-(2-(((4-carbamimidoylphenyl-2,3,5,6-d4)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acid
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Dabigatran-d4 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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Dabigatran-d4 usage and description
Dabigatran-d4 is a deuterated form of dabigatran, which is an oral anticoagulant medication used for the prevention of blood clots and stroke in patients with atrial fibrillation. It is also used for the treatment and prevention of deep vein thrombosis and pulmonary embolism.
The chemical name of dabigatran-d4 is N-[(1S)-1-(aminocarbonyl)-2-methylpropyl]-2-[[[4-[[[(hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1,3-thiazole-5-carboxamide-d4. It has a molecular weight of 491.64 g/mol and a chemical formula of C25H25D4N6O3S.
Dabigatran-d4 inhibits the activity of thrombin, which is a key enzyme involved in the blood coagulation process. It achieves this by binding to the active site of thrombin, thereby preventing the conversion of fibrinogen to fibrin, which is the final step in the formation of blood clots.
Dabigatran-d4 is administered orally in the form of capsules and is rapidly absorbed from the gastrointestinal tract. It has a half-life of approximately 12-17 hours and is primarily eliminated by the kidneys. Due to its high specificity for thrombin, dabigatran-d4 has fewer drug interactions compared to other anticoagulants, such as warfarin.
In conclusion, dabigatran-d4 is a deuterated form of dabigatran that is used as an anticoagulant medication for the prevention and treatment of blood clots and stroke. Its mechanism of action involves the inhibition of thrombin, and it has a high specificity and fewer drug interactions compared to other anticoagulants.
