Carmustine EP Impurity A; N,N′-Bis(2-chloroethyl)urea (ACI); Urea, 1,3-bis(2-chloroethyl)- (6CI, 7CI, 8CI); 1,3-Bis(2-chloroethyl)urea; NSC 36198,1,3-bis(2-chloroethyl)urea,"1,3-Bis(2-chloroethyl)urea is an impurity in the synthesis of Carmustine , an alkylating and carbamoylating nitrosourea compound. It interacts with DNA, RNA and proteins causing DNA interstrand cross linking which is cytotoxic and leads to apoptotic cell death.;Impurity in commercial preparations of Carmustine",Carmustine Therapeutic
