5-(N,N-Dimethyl)-amiloride-d6 Hydrochloride

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CS-T-100415

C₈H₆D₆ClN₇O • (HCl)

263.72 + (36.46)

[H]Cl.ClC1=NC(C(/N=C(N)\N)=O)=C(N)N=C1N(C([2H])([2H])[2H])C([2H])([2H])[2H]

Stable Isotopes

Refer MSDS for complete information.

3-amino-6-chloro-N-(diaminomethylene)-5-(dimethylamino-D6)pyrazine-2-carboxamide hydrochloride

"Isojima, Y., et al.: Proc. Natl. Acad. Sci. USA 106, 15744 (2009); Masereel, B., et al.: Eur J Med Chem 38, 547 (2003)"

3-Amino-N-(aminoiminomethyl)-6-chloro-5-(dimethylamino)-pyrazinecarboxamide-d6 Monohydrochloride; N-Amidino-3-amino-6-chloro-5-(dimethylamino)-pyrazinecarboxamide-d6 Monohydrochloride; (3-Amino-5-dimethylamino-6-chloropyrazinoyl)guanidine-d6 Hydrochloride

"5-(N,N-Dimethyl)-amiloride-d6 Hydrochloride is an isotopic analog of 5-(N,N-Dimethyl)-amiloride Hydrochloride (D470570), which has been used to investigate biochemical processes related to the circadian clock in mouse and human cell lines. It can also inhibit sodium-hydrogen exchangers (NHE). NHEs regulate sodium and pH in various tissues."

Refer MSDS for complete information.