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For Research Purposes only. Not for Personal use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
-
Product Code
CS-T-100712
M.F.
C37H38D5FN2O6
M.W.
635.78
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
tert-Butyl-4-hydroxy Atorvastatin-d5
References
"Smith, S. et al.: Am. J. Cardiol., 80, 10H (1997); Jacobsen, W. et al.: Drug Metab. Dispos., 28, 1369 (2000); Istvan, E. et al.: Science, 292, 1160 (2001); Tabernero, L. et al.: J. Biol. Chem., 278, 19933 (2003); Bratton, L. et al.: Bioorg. Med. Chem., 15"
"tert-Butyl-4-hydroxy Atorvastatin-d5 is the labeled analogue of tert-Butyl-4-hydroxy Atorvastatin (B692345), an intermediate in the synthesis of 4-Hydroxy Atorvastatin Hemicalcium Salt (H828961), a hydroxylated metabolite of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia."
Hazard Compound
Refer MSDS for complete information.
Overview
"tert-Butyl-4-hydroxy Atorvastatin-d5 is the labeled analogue of tert-Butyl-4-hydroxy Atorvastatin (B692345), an intermediate in the synthesis of 4-Hydroxy Atorvastatin Hemicalcium Salt (H828961), a hydroxylated metabolite of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia."
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