There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
-
Product Code
CS-T-101088
M.F.
C33H42D6O6Si2
M.W.
602.94
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
Di-(tert-Butyl-dimethylsilyl) Curcumin-d6
References
"Srinivasan, et al.: J. Pharm. Pharmacol., 5, 448 (1953); Tu, B., et al.: J .Cell Biol., 164, 341 (2004); Xu, G., et al.: Biochemistry, 44, 9817 (2005); Johnson, J., et al.: Cancer Lett., 255, 170 (2007)"
Synonyms
Di-(tert-Butyl-dimethylsilyl) Curcumin-d6
Application Notes
"Di-(tert-Butyl-dimethylsilyl) Curcumin-d6 is the labeled form of Di-(tert-Butyl-dimethylsilyl) Curcumin (D428050), which is a protected Curcumin (C838500). A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and I?B kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope."
Hazard Compound
Refer MSDS for complete information.
Overview
"Di-(tert-Butyl-dimethylsilyl) Curcumin-d6 is the labeled form of Di-(tert-Butyl-dimethylsilyl) Curcumin (D428050), which is a protected Curcumin (C838500). A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and I?B kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope."
![L-[1-13C]ribose](https://structures.clearsynth.com/CS-OC-00239.JPG)
