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Home Stable Isotopes CS-T-103313

LGX 818-d6

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Product Code: CS-T-103313 Stable Isotopes Research Use Only
LGX 818-d6
Category
Stable Isotopes
API Family
--
Product Code
CS-T-103313
Research Status
For Laboratory Use

LGX 818-d6

Stable Isotopes
Stock Status: : Enquire Live

CAT No.
CS-T-103313
CAS No.
2413673-31-9
Molecular Formula
C₂₂H₂₁D₆ClFN₇O₄S
Molecular Weight
546.05
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal or Veterinary use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
2413673-31-9
Product Code
CS-T-103313
M.F.
C₂₂H₂₁D₆ClFN₇O₄S
M.W.
546.05
Smiles
C[C@H](NC(OC([2H])([2H])[2H])=O)CNC1=NC=CC(C2=CN(C(C)C)N=C2C3=C(F)C(NS(=O)(C([2H])([2H])[2H])=O)=CC(Cl)=C3)=N1
Category
Stable Isotopes
API Family
-
Storage Condition
Refer MSDS for complete information.
IUPAC Name
Methyl-d3 (S)-(1-((4-(3-(5-chloro-2-fluoro-3-((methyl)sulfonamido-1,1,1-d3)phenyl)-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)propan-2-yl)carbamate ; Braftovi-d6 ; Encorafenib-d6
References
Huang, T., et al.: J. Hematol. Oncol., 6, 30 (2013); Stuart, D., et al. Method of treating a proliferative disease with a BRAF kinase inhibitor. PCT Int. Appl. WO 2013070996 A1 20130516. May 16, 2013
Synonyms
Methyl-d3 (S)-(1-((4-(3-(5-chloro-2-fluoro-3-((methyl)sulfonamido-1,1,1-d3)phenyl)-1-isopropyl-1H-pyrazol-4-yl)pyrimidin-2-yl)amino)propan-2-yl)carbamate ; Braftovi-d6 ; Encorafenib-d6
Application Notes
LGX 818-d6 is the labeled homolog of LGX 818 (L397655). LGX 818 is potent and selective BRAFV600E kinase inhibitor and can be used for the treatment of proliferative diseases such as solid tumor diseases.
Hazard Compound
Refer MSDS for complete information.
Overview
LGX 818-d6 is the labeled homolog of LGX 818 (L397655). LGX 818 is potent and selective BRAFV600E kinase inhibitor and can be used for the treatment of proliferative diseases such as solid tumor diseases.

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