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O=C(O)/C=C/C1=CC=CC(S(=O)(NC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])=O)=C1
API Family
Belinostat Acid
Storage Condition
Refer MSDS for complete information
IUPAC Name
(2E)-3-[3-[(Phenylamino)sulfonyl]phenyl]-2-propenoic Acid-d5; (E)-3-(3-(N-Phenylsulfamoyl)phenyl)acrylic Acid-d5
References
Chou, D.H., et al.: Chem. Biol., 19, 669 (2012); Hwang, J.J., et al.: Inves. New. Drugs., 30, 1434 (2012); Dizon, D.S., et al.: Gynecol. Oncol., 125, 367 (2012);
Synonyms
(2E)-3-[3-[(Phenylamino)sulfonyl]phenyl]-2-propenoic Acid-d5; (E)-3-(3-(N-Phenylsulfamoyl)phenyl)acrylic Acid-d5
Application Notes
Belinostat Acid-d5 is the labelled analogue of Belinostat Acid (B131485), a metabolite of Belinostat (B131400), a novel histone deacetylase 3 selective inhibitor, which protects the ฮฒ cells from cytokine-induced apoptosis.
Hazard Compound
Refer MSDS for complete information
Belinostat Acid-d5 is the labelled analogue of Belinostat Acid (B131485), a metabolite of Belinostat (B131400), a novel histone deacetylase 3 selective inhibitor, which protects the ฮฒ cells from cytokine-induced apoptosis.
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