Stable Isotopes Product Detail

Pralatrexate-15C5

Chemical Properties and Information

Product Code: CS-T-103769 Stable Isotopes
Pralatrexate-15C5
API Family
Pralatrexate
Product Code
CS-T-103769

Pralatrexate-15C5

Pralatrexate Stable Isotopes
Stock Status: : Enquire Live

CAT No.
CS-T-103769
CAS No.
146464-95-1(unlabelled)
Molecular Formula
C₁₈¹⁵C₅H₂₃N₇O₅
Molecular Weight
492.47
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
146464-95-1(unlabelled)
Product Code
CS-T-103769
M.F.
C₁₈¹⁵C₅H₂₃N₇O₅
M.W.
492.47
Smiles
C#CCC(C1=CC=C(C(N[15C@H]([15C](O)=O)[15CH2][15CH2][15C](O)=O)=O)C=C1)CC2=CN=C3C(C(N)=NC(N)=N3)=N2
Category
Stable Isotopes
API Family
Pralatrexate
Storage Condition
Refer MSDS for complete information.
IUPAC Name
N-[4-[1-[(2,4-Diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]-L-glutamic Acid-15C5; N-[4-[1-[(2,4-Diamino-6-pteridinyl)methyl]-3-butynyl]benzoyl]-L-glutamic Acid-15C5; 10-Propargyl-10-deazaaminopterin-15C5; Folotyn-15C5; PDX-15C5
References
Krug, L.M. et al.: Clin. Cancer Res., 6, 3493 (2000); O'Connor, O.A. et al.: Br. J. Haematol., 139, 425 (2007); O'Connor, O.A. et al.: J. Clin. Oncol., 29, 1182 (2011)
Synonyms
N-[4-[1-[(2,4-Diamino-6-pteridinyl)methyl]-3-butyn-1-yl]benzoyl]-L-glutamic Acid-15C5; N-[4-[1-[(2,4-Diamino-6-pteridinyl)methyl]-3-butynyl]benzoyl]-L-glutamic Acid-15C5; 10-Propargyl-10-deazaaminopterin-15C5; Folotyn-15C5; PDX-15C5
Application Notes
Pralatrexate-15C5 is labelled Pralatrexate (P700500) which is an antifolate with high affinity for the reduced folate carrier-type 1 that produces marked complete and durable remissions in a diversity of chemotherapy refractory cases of T-cell lymphoma.
Hazard Compound
Refer MSDS for complete information.
Overview
Pralatrexate-15C5 is labelled Pralatrexate (P700500) which is an antifolate with high affinity for the reduced folate carrier-type 1 that produces marked complete and durable remissions in a diversity of chemotherapy refractory cases of T-cell lymphoma.
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