CAS No.
1047634-65-0(unlabelled)
M.F.
C₁₄¹³C₄H₁₃D₃Cl₂F₂N₄O₂
Smiles
Cl[13C]([13CH]=N1)=[13C](C2=C(Cl)OC(C(N[C@H](CN)CC3=CC(F)=C(F)C=C3)=O)=C2)N1[13C]([2H])([2H])[2H]
Storage Condition
Refer MSDS for complete information
IUPAC Name
N-[(1S)-2-Amino-1-[(3,4-difluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-furancarboxamide-13C4d3; GSK 2141795C-13C4d3;
References
Seefield, M. A., et al.: PCT Int. Appl. (2008), WO 2008098104 A1 20080814; Liu, W., et al.: Toxicol. Appl. Pharmacol, 381, 114729 (2019);
Synonyms
N-[(1S)-2-Amino-1-[(3,4-difluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-furancarboxamide-13C4d3; GSK 2141795C-13C4d3;
Application Notes
Uprosertib-13C4d3 is the labelled analogue of Uprosertib (G797425), a potent and selective inhibitor of pan-Akt (1). Serine/threonine protein kinases, such as Akt, play important roles in cellular activities including cell survival and apoptosis.
Hazard Compound
Refer MSDS for complete information
Uprosertib-13C4d3 is the labelled analogue of Uprosertib (G797425), a potent and selective inhibitor of pan-Akt (1). Serine/threonine protein kinases, such as Akt, play important roles in cellular activities including cell survival and apoptosis.
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