Therapeutic Uses
,Hormones and the Endocrine System
Storage Condition
Store at refrigerator (2-8ยฐC) for long term storage
Synonyms
CloprostenolSodium
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
(5Z)-rel-Cloprostenol Sodium is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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(5Z)-rel-Cloprostenol Sodium usage and description
(5Z)-rel-Cloprostenol Sodium is a synthetic analogue of the naturally occurring prostaglandin F2ฮฑ. It is a potent luteolytic agent, meaning that it can induce the regression of the corpus luteum, which is a temporary endocrine structure in the ovaries that produces progesterone. This action can be used in both human and veterinary medicine.
In veterinary medicine, (5Z)-rel-Cloprostenol Sodium is commonly used to synchronize estrus in cattle, sheep, and pigs, as well as to induce parturition in cows. It can also be used to treat various reproductive disorders in these animals, such as pyometra (pus-filled uterus) and cystic ovarian disease. In humans, it is used to induce abortion and to treat postpartum hemorrhage.
The chemical structure of (5Z)-rel-Cloprostenol Sodium is similar to that of prostaglandin F2ฮฑ, but with modifications that increase its potency and duration of action. Specifically, the addition of a cyclopentane ring and a carboxylic acid group at the 15 position enhances its stability and binding affinity to the prostaglandin F2ฮฑ receptor.
Overall, (5Z)-rel-Cloprostenol Sodium is a valuable tool in reproductive management in both animals and humans, with its potent luteolytic effects and enhanced chemical stability making it a highly effective agent.
