Smiles
COC(C(OC)=C1OC)=CC2=C1C3=CC=C(OC)C(C=C3[C@@H](N)CC2)=O
IUPAC Name
"(S)-7-Amino-1,2,3,10-tetramethoxy-6,7-dihydrobenzo[a]heptalen-9(5H)-one"
References
"Sharma, S,, et al,: Biochem,, 49, 2932 (2010), Bartusik, D,, et al,: Bioorg, Chem,, 38, 1 (2010), Passarella, D,, et al,: Eur, J, Med, Chem,, 45, 219 (2010),"
Synonyms
N-Deacetyl Colchicine
Application Notes
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
Hazard Compound
Yes -Refer MSDS for accurate information
(-)-N-Deacetyl Colchicine is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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