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Fingolimod hydrochloride



Fingolimod hydrochloride Cas No.162359-56-0

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  • Synonyms:2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol;hydrochloride
  • Chemical Name:2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol;hydrochloride
  • Application Notes:"FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively)."
  • Product Category:Fingolimod Therapeutic



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    The product information for any accuracy or completeness is as per the existing knowledge furnished during the creation of the webpage.
    The purchaser, user or importer of record is responsible for determining the accuracy of items at the time of ordering as it may change without notice as per current product specification.
    This product is solely intended for research purposes and is not approved for human consumption.







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