CAS No.
[328385-86-0 (free base)]
Therapeutic Uses
Anti-Hypertensives
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
(S)-2-((3S,8aS)-3-(4-aminobutyl)-1,4-dioxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-4-phenylbutanoic acid compound with acetic acid (1:1)
Application Notes
Useful research chemical for a range of applications
Hazard Compound
No -Refer MSDS for accurate information
Lisinopril EP Impurity C Acetate is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Lisinopril EP Impurity C Acetate usage and description
Lisinopril EP impurity C is a commonly used pharmaceutical compound that belongs to the class of angiotensin-converting enzyme (ACE) inhibitors. It is used for the treatment of high blood pressure, heart failure, and to improve survival after a heart attack. Despite its effectiveness, the compound may contain impurities that affect its potency and safety. Lisinopril EP impurity C is one such impurity that can be found in small amounts in Lisinopril formulations.
Chemically, Lisinopril EP impurity C is known as (2S)-1-[2-[(1-carboxy-3-phenylpropyl)amino]-1-oxoethyl]-L-proline. It is a by-product of the synthesis of Lisinopril and can be formed during the manufacturing process or storage of the drug. The presence of impurity C in Lisinopril formulations can affect its efficacy and safety, hence it is important to monitor its levels and keep them within acceptable limits.
To ensure that Lisinopril EP impurity C does not cause harm to patients, regulatory bodies have set limits on its maximum allowed concentration in Lisinopril formulations. Pharmaceutical companies must adhere to these limits and ensure that their products meet the required quality standards. Analytical methods such as high-performance liquid chromatography (HPLC) are used to detect and quantify the impurity C levels in Lisinopril formulations.
In conclusion, Lisinopril EP impurity C is an important impurity that needs to be monitored in Lisinopril formulations to ensure their safety and efficacy. It is a by-product of the synthesis of Lisinopril and can be formed during the manufacturing process or storage of the drug. Regulatory bodies have set limits on its maximum allowed concentration, and analytical methods such as HPLC are used to detect and quantify its levels.
