Therapeutic Uses
Anti-Cancer / Oncology
Storage Condition
Store at refrigerator (2-8°C) for long term storage
Synonyms
Pemetrexed EP Impurity A
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Yes -Refer MSDS for accurate information
N-Methyl Pemetrexed is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
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If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
always, we appreciate your support.
N-Methyl Pemetrexed usage and description
N-Methyl Pemetrexed is a chemotherapy drug used to treat certain types of cancer, including mesothelioma and non-small cell lung cancer. It works by inhibiting the process of DNA synthesis, which slows down the growth and spread of cancer cells. This medication is a modified form of Pemetrexed, which was approved by the FDA in 2004.
N-Methyl Pemetrexed is available in the form of a powder that is reconstituted for intravenous use. The dosage and frequency of administration depend on the patient's condition and response to treatment. It is typically administered by a healthcare professional in a clinical setting.
Chemically, N-Methyl Pemetrexed is a folate antimetabolite that targets multiple enzymes involved in purine and pyrimidine synthesis. It inhibits the activity of thymidylate synthase, dihydrofolate reductase, and glycinamide ribonucleotide formyltransferase, which are essential for DNA synthesis. This results in arrested cell division and ultimately leads to cancer cell death.
Like any medication, N-Methyl Pemetrexed is associated with certain side effects, such as nausea, vomiting, diarrhea, fatigue, and decreased appetite. Patients may also experience bone marrow suppression, which can increase the risk of infection and bleeding. It is important to inform healthcare providers of any side effects experienced during treatment. Overall, N-Methyl Pemetrexed is an important chemotherapy drug that has helped many patients in their fight against cancer.
