Smiles
CC/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)/C3=CC=C(OCCN(C)C)C=C3
Therapeutic Uses
Anti-Cancer / Oncology,Anti-Cancer / Oncology,Anti Neo Plastic Agents
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
(Z)-2-(4-(1,2-Diphenylbut-1-en-1-yl)phenoxy)-N,N-dimethylethan-1-amine
References
"Sutherland, R,, et al,: Nature, 267, 434"
Synonyms
(Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine; Tamoxifen
Application Notes
"Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells."
Purity by HPLC
Not less than 95%
Hazard Compound
No -Refer MSDS for accurate information
InChI
InChI=1S/C8H10N4O2/c1-2-...
InChIKey
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
Tamoxifen is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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