Storage Condition
Refer MSDS for complete information
Synonyms
4-amino-3-(4-chlorophenyl)butanoic-2,2,4,4-d4 acid
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Baclofen D4 (2,2,4,4-D4) is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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Baclofen D4 (2,2,4,4-D4) usage and description
Baclofen D4 (2,2,4,4-D4) is a deuterated form of baclofen, which is a muscle relaxant and antispastic medication. Baclofen D4 is a labeled compound that is commonly used in research studies to study the pharmacokinetics and metabolism of baclofen.
Baclofen D4 is a GABA-B receptor agonist, which means that it binds to and activates GABA-B receptors in the brain and spinal cord. This leads to a decrease in the release of excitatory neurotransmitters, resulting in muscle relaxation and reduction of spasticity. Baclofen D4 has a half-life of approximately 4 hours and is metabolized primarily in the liver.
The deuterium labeling in Baclofen D4 allows for the differentiation between the labeled and unlabeled form of the compound, making it useful in pharmacokinetic studies. It is also used in the development of new drugs that target GABA-B receptors, as it allows researchers to study the effects of the drug on the body in a more precise manner.
In conclusion, Baclofen D4 is a useful compound for researchers studying the pharmacokinetics and metabolism of baclofen, as well as for the development of new drugs that target GABA-B receptors. Its chemical properties make it an effective tool in research studies, providing valuable insights into the mechanisms of action of muscle relaxants and antispastic medications.
