Product Detail
Curcumin-d6
Curcumin Stable Isotopes
Stock Status: In Stock
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For Research & Analytical Purposes. Not for Personal use.
Category
Stable Isotopes
API Family
Curcumin
Storage
Store at refrigerator (2-8°C) for long term storage
Hazard Information
Refer MSDS for accurate information.
Curcumin-d6 Product Information
Curcumin-d6 is listed under Stable Isotopes. It is associated with Curcumin and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-T-51318.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
Curcumin-d6
CAS No.
1246833-26-0
CAT No.
CS-T-51318
Molecular Formula
C21H14D6O6
Molecular Weight
374.42
Category
API Family
Storage Condition
Store at refrigerator (2-8°C) for long term storage
SMILES
O=C(CC(/C=C/C1=CC=C(O)C(OC([2H])([2H])[2H])=C1)=O)/C=C/C2=CC=C(O)C(OC([2H])([2H])[2H])=C2
IUPAC Name
1,7-bis[4-hydroxy-3-(trideuteriomethoxy)phenyl]hepta-1,6-diene-3,5-dione
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for accurate information.
Description
Overview
"Labelled Curcumin . A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope."
"Srinivasan, et al,: J, Pharm, Pharmacol,, 5, 448 (1953), Tu, B,, et al,: J ,Cell Biol,, 164, 341 (2004), Xu, G,, et al,: Biochemistry, 44, 9817"
Synonyms
1,7-bis[4-hydroxy-3-(trideuteriomethoxy)phenyl]hepta-1,6-diene-3,5-dione
Application Notes
"Labelled Curcumin . A natural phenolic compound. Potent anti-tumor agent having anti-inflammatory and anti-oxidant properties. Induces apoptosis in cancer cells and inhibits phorbol ester-induced protein kinase C (PKC) activity. Reported to inhibit production of inflammatory cytokines by peripheral blood monocytes and alveolar macrophages. Potent inhibitor of EGFR tyrosine kinase and IB kinase. Inhibits inducible nitric oxide synthase (iNOS), cycloxygenase and lipoxygenase. Easily penetrates into the cytoplasm of cells, accumulating in membranous structures such as plasma membrane, endoplasmic reticulum and nuclear envelope."
"Srinivasan, et al,: J, Pharm, Pharmacol,, 5, 448 (1953), Tu, B,, et al,: J ,Cell Biol,, 164, 341 (2004), Xu, G,, et al,: Biochemistry, 44, 9817"
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