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Stable Isotopes Product Detail
Home Stable Isotopes Fingolimod CS-T-55108

Fingolimod-d4 Hydrochloride

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Product Code: CS-T-55108 Stable Isotopes Research Use Only
Fingolimod-d4 Hydrochloride
Category
Stable Isotopes
API Family
Fingolimod
Product Code
CS-T-55108
Research Status
For Laboratory Use

Fingolimod-d4 Hydrochloride

Fingolimod Stable Isotopes
Stock Status: In Stock
Live

CAT No.
CS-T-55108
CAS No.
1346604-90-7
Molecular Formula
C₁₉H₃₀D₄ClNO₂
Molecular Weight
347.96
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There is no hazardous surcharge associated with this product.
There is no packaging charge associated with this product.
For Research Purposes only. Not for Personal or Veterinary use.
All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.
CAS No.
1346604-90-7
Product Code
CS-T-55108
M.F.
C₁₉H₃₀D₄ClNO₂
M.W.
347.96
Category
Stable Isotopes
API Family
Fingolimod
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
2-Amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol-D4 Hydrochloride
References
"Brinkmann, V,, et al,: Transplantation, 72, 764 (2001), Brinkmann, et al,: J, Biol, Chem,, 277, 24, 21453 (2002), Mtaloubian, M,, et al,: Nature, 427, 355 (2004), "
Synonyms
Not available
Application Notes
"A labelled derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively)."
Purity by HPLC
Not less than 90%
Hazard Compound
Refer MSDS for accurate information.
Overview
"A labelled derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively)."

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