Storage Condition
Refer MSDS for complete information
Synonyms
D-Glucose-4,5-d2, 478529-48-5
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
D-Glucose-4,5-d2 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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D-Glucose-4,5-d2 usage and description
D-Glucose-4,5-d2 is a stable isotopic tracer compound used in metabolic research. It is a deuterated form of D-glucose, a monosaccharide that is essential for the proper functioning of the human body. D-Glucose-4,5-d2 is a valuable tool for studying glucose metabolism in vivo and in vitro, as it allows for the tracking and quantification of glucose utilization and conversion pathways.
Chemically, D-Glucose-4,5-d2 is identical to regular D-glucose, except that two of the hydrogen atoms on carbons 4 and 5 are replaced with deuterium atoms. This isotopic substitution does not affect the chemical properties of the molecule, but it does alter its physical properties, such as its mass and infrared spectrum. These differences can be exploited for analytical purposes, allowing researchers to distinguish between the labeled and unlabeled forms of glucose.
D-Glucose-4,5-d2 is typically administered to subjects in the form of a solution or infusion. It can be used in a variety of metabolic studies, including glucose uptake and utilization, gluconeogenesis, and glycogen synthesis. By measuring the concentration and distribution of the labeled glucose in various tissues and metabolic pathways, researchers can gain insight into the mechanisms underlying glucose metabolism and its role in health and disease.
In summary, D-Glucose-4,5-d2 is a powerful tool for studying glucose metabolism and related metabolic processes. Its unique isotopic properties allow for precise tracking and quantification of glucose utilization and conversion pathways, making it an invaluable resource for metabolic research.
