Smiles
ClC1=CC=C2C(CCC3=CC=CN=C3C2(C4CCN(CC4)C)O)=C1
Therapeutic Uses
Antihistamine
Storage Condition
Store at refrigerator (2-8°C) for long term storage
IUPAC Name
8-chloro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol
References
"Zhong, D,, et al,: Pharmazie, 49, 736 (1994), Squella, J,, et al,: Talanta, 43, 2029 (1996), Ruperez, F,, et al,: J, Pharm, Biomed, Anal,, 29, 35 (2002), "
Synonyms
8-chloro-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol
Application Notes
11-Hydroxy-N-methyl Dihydroloratadine is an impurity of Loratadine .
Purity by HPLC
Not less than 95 %
Hazard Compound
No -Refer MSDS for accurate information
11-Hydroxy-N-methyl Dihydro Loratadine is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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11-Hydroxy-N-methyl Dihydro Loratadine usage and description
11-Hydroxy-N-methyl Dihydro Loratadine, also known as Desloratadine, is a second-generation antihistamine used to treat allergies such as hay fever, hives, and allergic rhinitis. This medication works by blocking the release of histamine, a chemical that causes allergic reactions in the body.
Desloratadine is available in both tablet and syrup forms and is typically taken once a day. The dosage may vary depending on the individual's age, weight, and medical condition. It is recommended to take this medication with or without food and to avoid drinking alcohol while taking it.
Chemically, Desloratadine is a metabolite of Loratadine, which means that it is formed after the body processes Loratadine. It has a molecular weight of 310.82 g/mol and a chemical formula of C19H19ClN2. This medication is metabolized in the liver and eliminated from the body through urine and feces.
Desloratadine is considered to be a safe and effective medication for the treatment of allergies. However, like any medication, it may cause side effects such as drowsiness, dry mouth, headache, and nausea. It is important to consult with a healthcare provider before taking this medication, especially if you have any underlying medical conditions or are taking other medications.
