M.F.
C₁₈H₁₀D₈ClN₃O + x(HCl)
Therapeutic Uses
Anti anxiety and Anti Psychotic
Storage Condition
Store at freezer (-20°C) for long term storage
Synonyms
2-chloro-11-(4-methylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)dibenzo[b,f][1,4]oxazepine hydrochloride
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
Loxapine-d8 Hydrochloride is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
We have invested in the highest quality packaging materials and use international logistics partners to service our customers. While all
possible precautions have been taken to deliver the required product(s), there may be some rare situations when our product does not
meet your requirements. Should that arise, please contact us with your concerns and we will endeavour to address them on a priority
basis. If there is no other option, we will either replace your product(s) or issue a refund or account credit, whichever you prefer.
If there is an issue with one or more of our products, our policy is that it must be reported to us within 45 days of your receiving shipment.
While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
always, we appreciate your support.
Loxapine-d8 Hydrochloride usage and description
Loxapine-d8 hydrochloride is a deuterated form of the antipsychotic medication loxapine hydrochloride. Deuterated compounds are molecules in which one or more hydrogen atoms have been replaced with deuterium, a stable isotope of hydrogen. Loxapine-d8 hydrochloride is used in scientific research as a labeled internal standard for the quantification of loxapine in biological matrices such as blood, plasma, and urine.
Loxapine hydrochloride is a dibenzoxazepine derivative that acts as a dopamine receptor antagonist. It is commonly used for the treatment of psychotic disorders such as schizophrenia and bipolar disorder. Loxapine-d8 hydrochloride has the same chemical structure as loxapine hydrochloride, but with eight deuterium atoms incorporated into the molecule. This modification results in a slight increase in the molecular weight of the compound, which can be detected using mass spectrometry.
The use of loxapine-d8 hydrochloride as an internal standard allows for accurate and precise measurements of loxapine levels in biological samples. This is important in pharmacokinetic and pharmacodynamic studies, as well as in therapeutic drug monitoring. The deuterium-labeled compound is added to the sample prior to analysis, and the ratio of labeled to unlabeled loxapine is then measured. This approach enables researchers to determine the concentration of loxapine in the sample with high accuracy and reproducibility.
In conclusion, loxapine-d8 hydrochloride is a useful tool for the quantification of loxapine in biological samples. Its chemical properties and labeled structure make it an ideal internal standard for mass spectrometry-based analysis, aiding in the study and treatment of psychotic disorders.
